If a patient has ANY previous fasting or direct laboratory result of LDL-C >= 190 mg/dL, report the highest value >= 190 mg/dL. The measure can be reported for all patients with a documented fasting or direct LDL-C level recorded as follows: Encounter, performed: initial or established office visit, face-to-face interaction, preventive care services, or annual wellness visit In order for the patient to be included in the denominator, the patient must have ONE denominator-eligible visit, defined as follows: If NO, patient does NOT meet Denominator criteria and is NOT eligible for measure inclusion If YES, meets Denominator Population 3 risk category Patients aged 40 to 75 years at the beginning of the measurement period with Type 1 or Type 2 diabetes and with a LDL-C result of 70 -189 mg/dL recorded as the highest fasting or direct laboratory test result in the measurement year or during the two years prior to the beginning of the measurement period If YES, meets Denominator Population 2 risk category Patients aged >= 21 years at the beginning of the measurement period who have ever had a fasting or direct laboratory test result of LDL-C >= 190 mg/dL or were previously diagnosed with or currently have an active diagnosis of familial or pure hypercholesterolemia If YES, meets Denominator Population 1 risk category

Patients with diabetes who have the most recent fasting or direct LDL-C laboratory test result = 21 years at the beginning of the measurement period with clinical ASCVD Patients with end-stage renal disease (ESRD) Patients with active liver disease or hepatic disease or insufficiency Patients who are receiving palliative or hospice care Patients with adverse effect, allergy, or intolerance to statin medication Patients who are actively using or who receive an order (prescription) for statin therapy at any point during the measurement period Patients who have a diagnosis of rhabdomyolysis Patients who have a diagnosis of pregnancy *Adults aged 40-75 years with a diagnosis of diabetes with a fasting or direct LDL-C level of 70-189 mg/dLĪll patients aged 21 years and older at the beginning of the measurement period with a patient encounter during the measurement periodĪll patients who meet one or more of the following criteria (considered at 'high risk' for cardiovascular events, under ACC/AHA guidelines):ġ) Patients aged >= 21 years at the beginning of the measurement period with clinical ASCVD diagnosisĢ) Patients aged >= 21 years at the beginning of the measurement period who have ever had a fasting or direct laboratory result of LDL-C >=190 mg/dL or were previously diagnosed with or currently have an active diagnosis of familial or pure hypercholesterolemiaģ) Patients aged 40 to 75 years at the beginning of the measurement period with Type 1 or Type 2 diabetes and with an LDL-C result of 70-189 mg/dL recorded as the highest fasting or direct laboratory test result in the measurement year or during the two years prior to the beginning of the measurement period *Adults aged >= 21 years who have ever had a fasting or direct low-density lipoprotein cholesterol (LDL-C) level >= 190 mg/dL or were previously diagnosed with or currently have an active diagnosis of familial or pure hypercholesterolemia OR *Adults aged >= 21 years who were previously diagnosed with or currently have an active diagnosis of clinical atherosclerotic cardiovascular disease (ASCVD) OR Percentage of the following patients - all considered at high risk of cardiovascular events - who were prescribed or were on statin therapy during the measurement period:

High intensity statin list